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A PKGIα activator; induces relaxation in U-46619-precontracted mesenteric arteries isolated from wild-type, but not oxidation-insensitive Cys42Ser PKGIα knock-in, mice in a concentration-dependent manner; induces oxidation of PKGIα in the aorta in a mouse model of angiotensin II-induced hypertension at 14.8 mg/kg; decreases mean arterial pressure in the same model at 20 mg/kg per day for 4 days
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
An activator of the STING pathway induces secretion of IFN-B in human PBMCs (EC50 130 nM) increases serum levels of Ifn-B Il-6 Tnf and Cxcl1 in wild-type but not Sting-/- mice at 2.5 mg/kg inhibits the cytopathic effect of HCoV-229E in infected MRC-5 cells (EC50 3 nM) decreases the level of SARS-CoV-2 RNA in primary human bronchial airway epithelial cells in an air-liquid interface assay decreases tumor volume and increases survival in a CT26 murine colorectal cancer model at 3 mg/kg this compound is expected to exist in one or both tautomeric forms
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Empirical Formula (Hill Notation): C9H9Cl2N3, Molecular Weight: 230.09, 1.0 mg/mL in Methanol. Clonidine is a pharmaceutical drug used to treat a wide variety of conditions including hypertension, ADHD, insomnia, chemical withdrawal, and anxiety. Clonidine is often prescribed in combination with other drugs, depending on the clinical condition. This analytical reference standard is suitable for use as starting material in calibrators or controls for a variety of LC/MS or GC/MS applications from forensic analysis and clinical toxicology to pharmaceutical research.
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Alco-Screen 02 is a simple, cost effective tool used to monitor alcohol consumption as part of a comprehensive Zero Tolerance testing program. Alco-Screen 02 is a Conforming Product for US Department of Transportation mandated testing of all transportation and safety sensitive employees for blood alcohol concentrations above the federally mandated zero tolerance level of 0.02%. Alco-Screen 02 is FDA 510(k) cleared for home use and is CLIA waived.
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
(25/Pack) CLIAwaived, Inc. IDTC-II Instant Drug Test Card - Tests for AMP500 / BAR300 / BUP10 / BZO300 / COC150 / MDMA500 / MET500 / MTD300 / OPI300 / OXY100 / PCP25 / THC50 + Adulterants+ CRE, pH, OX. The newly designed IDTC-II dip card features a hermetic seal to prevent the card from flooding. The device features a flat and separate cap so it can be easily photographed without contamination.
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
(50/Pack) CLIA waived single urine dip stick test for Oxycodone. Read results from 5-60 minutes. New hermetically sealed plastic housing prevents dip card from flooding. Easy to read. Negative results as soon as 1 minute. Offers improved accuracy and sensitivity testing.
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Accutest CLIA Waived 12 panel drug test cup is a rapid, one-step qualitative urine drug test that uses a visually read competitive binding immunoassay method for screening multiple drugs and drug metabolites in human urine without the need of instrumentation.
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
The Meso Scale Discovery Muscle Injury Panel 3 Mouse Kit is designed to measure biomarkers associated with muscle injury and inflammation in mouse samples The kit contains a 96-well plate coated with capture antibodies for mouse Myoglobin Fatty Acid Binding Protein 3 and Creatine Kinase MM It utilizes electrochemiluminescent detection technology for high sensitivity and broad dynamic range The kit includes all necessary reagents and can process up to 40 samples in duplicate It is intended for research use only
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More